Pentobarbital will decrease the level or effect of ketoconazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. buprenorphine transdermal and pentobarbital both increase sedation. Avoid or Use Alternate Drug. Limit use to patients for whom alternative treatment options are inadequate pentobarbital will decrease the level or effect of atogepant by https://tvsocialnews.com/story5861019/pentobarbital-cosa-%C3%88-una-panoramica