Notwithstanding many setbacks, several MDM2 inhibitors have now progressed into late-phase medical progress. New procedures have also been created to improve the efficacy of MDM2 inhibitors also to mitigate their on-target toxicity. In this assessment, we summarize the progress and difficulties in the development of the MDM2 targeted therapy. If https://charlesp530akv7.wikiconverse.com/user