Not all individuals with CLL require therapy. Inspite of all latest developments, the iwCLL continue to suggests watchful observation for patients with asymptomatic disorder.86 This recommendation is predicated on not less than two randomized trials comparing observation to possibly chlorambucil monotherapy or fludarabine, cyclophosphamide and rituximab (FCR).103,104 The two trials https://jamest764sbi1.aboutyoublog.com/profile